A dominant gene for developmental dyslexia on chromosome 3

A dominant gene for developmental dyslexia on chromosome 3.

Developmental dyslexia is a neurofunctional disorder characterised by an unexpected difficulty in learning to read and write despite adequate intelligence, motivation, and education. Previous studies have suggested mostly quantitative susceptibility loci for dyslexia on chromosomes 1, 2, 6, and 15, but no genes have been identified yet. We studied a large pedigree, ascertained from 140 families...

Original articles A dominant gene for developmental dyslexia on chromosome 3

Developmental dyslexia is a neurofunctional disorder characterised by an unexpected diYculty in learning to read and write despite adequate intelligence, motivation, and education. Previous studies have suggested mostly quantitative susceptibility loci for dyslexia on chromosomes 1, 2, 6, and 15, but no genes have been identified yet. We studied a large pedigree, ascertained from 140 families c...

Developmental dyslexia.

T he term developmental dyslexia ("specific reading retardation") refers to an unexpected difficulty in reading in children and adults who otherwise possess the intelligence, motivation, and schooling considered necessary for accurate and fluent reading. The concept has had a chequered career, with debates about its definition, origin, and causes, and indeed about its validity as a distinct ent...

Developmental Dyslexia

The possible causes and correlates of such difficulty have been the focus of a great deal of theorizing since before the turn of the twentieth century, when W. Pringle Morgan (1896) described a 14-year-old boy named Percy who suffered from pronounced difficulty learning to read and spell, despite normal achievement in other academic areas. Because he could find no evidence of definitive brain i...

Developmental Dyslexia